# Beneath the surface: endosomal GPCR signaling

*PRI Rank #19 · Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026/rank-19*

| Field | Value |
| --- | --- |
| Rank | #19 |
| 18m citations | 24 |
| Journal | Trends in Biochemical Sciences |
| Year | 2024 |
| DOI | 10.1016/j.tibs.2024.03.006 |
| Corresponding authors | A. Thomsen |
| Institution | New York University, United States |

**Ranking page:** [Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026](https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026)

**Paper link:** [10.1016/j.tibs.2024.03.006](https://doi.org/10.1016/j.tibs.2024.03.006)

## Topics

Endosomal signaling · G protein-coupled receptor (GPCR) · G protein-coupled receptor (GPCR) · Endosomal signaling · Receptor trafficking · sustained signaling · β-arrestin · Receptor trafficking · compartmentalized signaling · Functional selectivity

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```