# Profiling the proximal proteome of the activated μ-opioid receptor

*PRI Rank #18 · Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026/rank-18*

| Field | Value |
| --- | --- |
| Rank | #18 |
| 18m citations | 25 |
| Journal | Nature Chemical Biology |
| Year | 2024 |
| DOI | 10.1038/s41589-024-01588-3 |
| Corresponding authors | Mark von Zastrow, Ruth Hüttenhain |
| Institution | University of California, San Francisco, United States |

**Ranking page:** [Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026](https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026)

**Paper link:** [10.1038/s41589-024-01588-3](https://doi.org/10.1038/s41589-024-01588-3)

## Topics

μ-opioid receptor · proximal proteome · proximity labeling · receptor activation · protein-protein interactions · Opioid receptor signaling · GPCR interactome · mass spectrometry proteomics · Receptor trafficking · signaling complexes

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```