# Integrated network toxicology, molecular docking, and in vivo experiments to elucidate molecular mechanism of aflatoxin B1 hepatotoxicity

*PRI Rank #12 · Topics and Trends in Most Cited Mycotoxins in Agriculture and Food Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/mycotoxins-in-agriculture-and-food/2026/rank-12*

| Field | Value |
| --- | --- |
| Rank | #12 |
| 18m citations | 27 |
| Journal | Ecotoxicology and Environmental Safety |
| Year | 2024 |
| DOI | 10.1016/j.ecoenv.2024.116278 |
| Corresponding authors | Xuemei Zhang |
| Institution | Yanbian University, China |

**Ranking page:** [Topics and Trends in Most Cited Mycotoxins in Agriculture and Food Papers, Class of 2026](https://pri.pepkio.com/top-papers/mycotoxins-in-agriculture-and-food/2026)

**Paper link:** [10.1016/j.ecoenv.2024.116278](https://doi.org/10.1016/j.ecoenv.2024.116278)

## Topics

Aflatoxin B1 · Hepatotoxicity · network toxicology · molecular docking · PI3K/AKT/mTOR pathway · MAPK signaling pathway · FOXO1 signaling pathway · hepatocyte apoptosis · EGFR · ERK · PIK3CG · MAPK8 · HSP90AA1 · PPARA · IGF1 · caspase3 · Bcl2/Bax ratio · climate change impact on mycotoxins · liver damage biomarkers · environmental pollutant toxicity

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Mycotoxins in Agriculture and Food Papers, Class of 2026. https://pri.pepkio.com/top-papers/mycotoxins-in-agriculture-and-food/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```