# Rapid and sensitive detection of genome contamination at scale with FCS-GX

*PRI Rank #2 · Topics and Trends in Most Cited Molecular Biology Techniques and Applications Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/molecular-biology-techniques-and-applications/2026/rank-2*

| Field | Value |
| --- | --- |
| Rank | #2 |
| 18m citations | 197 |
| Journal | Genome biology |
| Year | 2024 |
| DOI | 10.1186/s13059-024-03198-7 |
| Corresponding authors | Terence D. Murphy |
| Institution | National Institutes of Health, United States |

**Ranking page:** [Topics and Trends in Most Cited Molecular Biology Techniques and Applications Papers, Class of 2026](https://pri.pepkio.com/top-papers/molecular-biology-techniques-and-applications/2026)

**Paper link:** [10.1186/s13059-024-03198-7](https://doi.org/10.1186/s13059-024-03198-7)

## Topics

Foreign Contamination Screen (FCS-GX) · Foreign Contamination Screen (FCS-GX) · genome contamination detection · contaminant sequence removal · Genome assembly · NCBI RefSeq · Genome assembly · artificially fragmented genomes · sensitivity and specificity testing · high-throughput genome screening · contamination quantification · genome assembly quality control

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Molecular Biology Techniques and Applications Papers, Class of 2026. https://pri.pepkio.com/top-papers/molecular-biology-techniques-and-applications/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```