# High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer

*PRI Rank #11 · Topics and Trends in Most Cited Molecular Biology Techniques and Applications Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/molecular-biology-techniques-and-applications/2026/rank-11*

| Field | Value |
| --- | --- |
| Rank | #11 |
| 18m citations | 47 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-48917-7 |
| Corresponding authors | Scott Hickey, Jan Karlseder |
| Institution | Salk Institute for Biological Studies, United States |

**Ranking page:** [Topics and Trends in Most Cited Molecular Biology Techniques and Applications Papers, Class of 2026](https://pri.pepkio.com/top-papers/molecular-biology-techniques-and-applications/2026)

**Paper link:** [10.1038/s41467-024-48917-7](https://doi.org/10.1038/s41467-024-48917-7)

## Topics

Telo-seq · Nanopore sequencing · Direct RNA sequencing · telomere length measurement · chromosome arm-specific telomere length · allele-specific telomere length · telomere length heterogeneity · telomere shortening · population doubling · telomerase-positive cancer · ALT-positive cancer · alternative lengthening of telomeres · telomere biology

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Molecular Biology Techniques and Applications Papers, Class of 2026. https://pri.pepkio.com/top-papers/molecular-biology-techniques-and-applications/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```