# Orientation-independent-DIC imaging reveals that a transient rise in depletion attraction contributes to mitotic chromosome condensation

*PRI Rank #19 · Topics and Trends in Most Cited Microtubule and mitosis dynamics Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/microtubule-and-mitosis-dynamics/2026/rank-19*

| Field | Value |
| --- | --- |
| Rank | #19 |
| 18m citations | 25 |
| Journal | Proceedings of the National Academy of Sciences |
| Year | 2024 |
| DOI | 10.1073/pnas.2403153121 |
| Corresponding authors | Michael Shribak, Kazuhiro Maeshima |
| Institution | National Institute of Genetics, Japan |

**Ranking page:** [Topics and Trends in Most Cited Microtubule and mitosis dynamics Papers, Class of 2026](https://pri.pepkio.com/top-papers/microtubule-and-mitosis-dynamics/2026)

**Paper link:** [10.1073/pnas.2403153121](https://doi.org/10.1073/pnas.2403153121)

## Topics

orientation-independent-DIC imaging · depletion attraction · Macromolecular crowding · Chromosome condensation · condensins · topoisomerase IIα · chromosome milieu · Confocal microscopy · optical path differences · molecular density · Nuclear envelope breakdown · chromatin liquid droplets · hypotonic treatment · hypertonic treatment · cell volume decrease · chromatin stiffness · prophase to anaphase progression · telophase decondensation · in vitro chromatin assembly · Macromolecular crowding

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Microtubule and mitosis dynamics Papers, Class of 2026. https://pri.pepkio.com/top-papers/microtubule-and-mitosis-dynamics/2026. Accessed 2026-07-23.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```