# Integrative analysis of genomic and epigenomic regulation reveals miRNA mediated tumor heterogeneity and immune evasion in lower grade glioma

*PRI Rank #7 · Topics and Trends in Most Cited MicroRNA in disease regulation Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/microrna-in-disease-regulation/2026/rank-7*

| Field | Value |
| --- | --- |
| Rank | #7 |
| 18m citations | 56 |
| Journal | Communications Biology |
| Year | 2024 |
| DOI | 10.1038/s42003-024-06488-9 |
| Corresponding authors | Zhen Yang, Kun Lv, Hui Yang |
| Institution | Fudan University, China |

**Ranking page:** [Topics and Trends in Most Cited MicroRNA in disease regulation Papers, Class of 2026](https://pri.pepkio.com/top-papers/microrna-in-disease-regulation/2026)

**Paper link:** [10.1038/s42003-024-06488-9](https://doi.org/10.1038/s42003-024-06488-9)

## Topics

MicroRNA · DNA methylation · copy number variation · miRNA expression dysregulation · lower grade glioma · Promoter methylation · Integrative multi-omics analysis · glioma subtypes · immune evasion · miRNA regulatory network · immunotherapy response · cell migration · Cell invasion · cell proliferation · tumor heterogeneity · prognosis-related miRNAs · Immune regulation · patient stratification · biomarkers for immunotherapy

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited MicroRNA in disease regulation Papers, Class of 2026. https://pri.pepkio.com/top-papers/microrna-in-disease-regulation/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```