# Harnessing extracellular vesicle heterogeneity for diagnostic and therapeutic applications

*PRI Rank #2 · Topics and Trends in Most Cited MicroRNA in disease regulation Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/microrna-in-disease-regulation/2026/rank-2*

| Field | Value |
| --- | --- |
| Rank | #2 |
| 18m citations | 154 |
| Journal | Nature Nanotechnology |
| Year | 2024 |
| DOI | 10.1038/s41565-024-01774-3 |
| Corresponding authors | Randy P. Carney, Steven C. George |
| Institution | University of California, Davis, United States |

**Ranking page:** [Topics and Trends in Most Cited MicroRNA in disease regulation Papers, Class of 2026](https://pri.pepkio.com/top-papers/microrna-in-disease-regulation/2026)

**Paper link:** [10.1038/s41565-024-01774-3](https://doi.org/10.1038/s41565-024-01774-3)

## Topics

extracellular vesicles · EV heterogeneity · diagnostic applications · therapeutic applications · EV subpopulations · biomarker discovery · EV cargo · EV isolation methods · EV characterization · targeted EV delivery · EV engineering · Liquid biopsy · drug delivery vehicles · EV surface markers · tissue-specific EVs

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited MicroRNA in disease regulation Papers, Class of 2026. https://pri.pepkio.com/top-papers/microrna-in-disease-regulation/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```