# Engineering a xylose fermenting yeast for lignocellulosic ethanol production

*PRI Rank #20 · Topics and Trends in Most Cited Microbial Metabolic Engineering and Bioproduction Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/microbial-metabolic-engineering-and-bioproduction/2026/rank-20*

| Field | Value |
| --- | --- |
| Rank | #20 |
| 18m citations | 37 |
| Journal | Nature Chemical Biology |
| Year | 2024 |
| DOI | 10.1038/s41589-024-01771-6 |
| Corresponding authors | Sheng Yang |
| Institution | Chinese Academy of Sciences, China |

**Ranking page:** [Topics and Trends in Most Cited Microbial Metabolic Engineering and Bioproduction Papers, Class of 2026](https://pri.pepkio.com/top-papers/microbial-metabolic-engineering-and-bioproduction/2026)

**Paper link:** [10.1038/s41589-024-01771-6](https://doi.org/10.1038/s41589-024-01771-6)

## Topics

Sugar co-utilization · Ethanol production · Metabolic engineering · Saccharomyces cerevisiae · xylose reductase · xylitol dehydrogenase · xylulokinase · pentose phosphate pathway · cofactor imbalance · NADH/NADPH · Heterologous expression · Pichia stipitis · xylose isomerase · Fermentation · Engineered yeast

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Microbial Metabolic Engineering and Bioproduction Papers, Class of 2026. https://pri.pepkio.com/top-papers/microbial-metabolic-engineering-and-bioproduction/2026. Accessed 2026-07-29.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```