# Safety and potential effects of intrathecal injection of allogeneic human umbilical cord mesenchymal stem cell-derived exosomes in complete subacute spinal cord injury: a first-in-human, single-arm, open-label, phase I clinical trial

*PRI Rank #5 · Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026/rank-5*

| Field | Value |
| --- | --- |
| Rank | #5 |
| 18m citations | 63 |
| Journal | Stem Cell Research & Therapy |
| Year | 2024 |
| DOI | 10.1186/s13287-024-03868-0 |
| Corresponding authors | Reza Heidari, Saeed Oraee‐Yazdani |
| Institution | AJA University of Medical Sciences, Iran |

**Ranking page:** [Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026](https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026)

**Paper link:** [10.1186/s13287-024-03868-0](https://doi.org/10.1186/s13287-024-03868-0)

## Topics

Intrathecal injection · Umbilical cord MSC-derived exosomes · Umbilical cord MSC-derived exosomes · complete subacute spinal cord injury · Phase I clinical trial · Ultracentrifugation · American Spinal Injury Association Impairment Scale · Spinal Cord Independence Measure (SCIM-III) · neurogenic bowel dysfunction (NBD) score · modified Ashworth scale (MAS) · ASIA pinprick score · ASIA light touch score · axon regeneration · Paracrine activity · lower urinary tract function · Functional recovery · sensory improvement

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026. https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```