# 3D culture of alginate-hyaluronic acid hydrogel supports the stemness of human mesenchymal stem cells

*PRI Rank #19 · Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026/rank-19*

| Field | Value |
| --- | --- |
| Rank | #19 |
| 18m citations | 31 |
| Journal | Scientific Reports |
| Year | 2024 |
| DOI | 10.1038/s41598-024-54912-1 |
| Corresponding authors | Parinya Noisa |
| Institution | Suranaree University of Technology, Thailand |

**Ranking page:** [Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026](https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026)

**Paper link:** [10.1038/s41598-024-54912-1](https://doi.org/10.1038/s41598-024-54912-1)

## Topics

alginate-hyaluronic acid hydrogel · 3D cell culture · Mesenchymal stem cells · stemness maintenance · Cell spheroids · OCT-4 · NANOG · SOX2 · SIRT1 · YAP · TAZ · Ki67 · hTERT · telomere relative length · cell encapsulation · extracellular matrix mimicry · Gelatin methacryloyl (GelMA) · Live/Dead viability assay · Scaffolds

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026. https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```