# Exosome-coated oxygen nanobubble-laden hydrogel augments intracellular delivery of exosomes for enhanced wound healing

*PRI Rank #1 · Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026/rank-1*

| Field | Value |
| --- | --- |
| Rank | #1 |
| 18m citations | 141 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-47696-5 |
| Corresponding authors | Joseph Irudayaraj |
| Institution | University of Illinois at Urbana-Champaign, United States |

**Ranking page:** [Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026](https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026)

**Paper link:** [10.1038/s41467-024-47696-5](https://doi.org/10.1038/s41467-024-47696-5)

## Topics

exosome-coated oxygen nanobubbles · Adipose-derived mesenchymal stem cells · hypoxia-induced endocytic recycling · polyvinyl alcohol/gelatin hybrid hydrogel · intracellular cargo delivery · chronic hypoxia · wound angiogenesis · self-healing hydrogel · hydrogen peroxide decomposition · hemostasis · exosome therapeutic cargo · Full-thickness wound model · wound inflammation · hypoxic tissue delivery · crosslinking bonds · microRNA delivery

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026. https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```