# Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial

*PRI Rank #11 · Topics and Trends in Most Cited Malaria Research and Control Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/malaria-research-and-control/2026/rank-11*

| Field | Value |
| --- | --- |
| Rank | #11 |
| 18m citations | 33 |
| Journal | The Lancet Infectious Diseases |
| Year | 2024 |
| DOI | 10.1016/s1473-3099(24)00312-8 |
| Corresponding authors | Angela M. Minassian |
| Institution | University of Oxford, United Kingdom |

**Ranking page:** [Topics and Trends in Most Cited Malaria Research and Control Papers, Class of 2026](https://pri.pepkio.com/top-papers/malaria-research-and-control/2026)

**Paper link:** [10.1016/s1473-3099(24)00312-8](https://doi.org/10.1016/s1473-3099(24)00312-8)

## Topics

RH5.1 · Matrix-M adjuvant · blood-stage malaria vaccine · Plasmodium falciparum · phase 1b trial · dose-escalation · age de-escalation · delayed-fractional third dose regimen · anti-RH5.1 serum IgG · growth inhibition activity · GIA · antibody avidity · RH5-specific T cell responses · malaria-endemic population · Tanzanian children · pre-erythrocytic vaccines · polyclonal IgG · non-human primate challenge model · Delayed third dose regimen · malaria pre-exposure

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Malaria Research and Control Papers, Class of 2026. https://pri.pepkio.com/top-papers/malaria-research-and-control/2026. Accessed 2026-07-23.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```