# Metabolic dysfunction-associated steatotic liver disease: heterogeneous pathomechanisms and effectiveness of metabolism-based treatment

*PRI Rank #5 · Topics and Trends in Most Cited Liver Disease Diagnosis and Treatment Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/liver-disease-diagnosis-and-treatment/2026/rank-5*

| Field | Value |
| --- | --- |
| Rank | #5 |
| 18m citations | 288 |
| Journal | The Lancet Diabetes & Endocrinology |
| Year | 2024 |
| DOI | 10.1016/s2213-8587(24)00318-8 |
| Corresponding authors | Norbert Stefan |
| Institution | University Hospital Tübingen, Germany |

**Ranking page:** [Topics and Trends in Most Cited Liver Disease Diagnosis and Treatment Papers, Class of 2026](https://pri.pepkio.com/top-papers/liver-disease-diagnosis-and-treatment/2026)

**Paper link:** [10.1016/s2213-8587(24)00318-8](https://doi.org/10.1016/s2213-8587(24)00318-8)

## Topics

Metabolic dysfunction-associated steatotic liver disease · Metabolic dysfunction-associated steatotic liver disease · heterogeneous pathomechanisms · metabolism-based treatment · Hepatic steatosis · insulin resistance · Lipid metabolism · mitochondrial dysfunction · oxidative stress · inflammatory pathways · Fibrosis progression · metabolic syndrome · therapeutic targets · personalized medicine approaches

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Liver Disease Diagnosis and Treatment Papers, Class of 2026. https://pri.pepkio.com/top-papers/liver-disease-diagnosis-and-treatment/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```