# A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis

*PRI Rank #4 · Topics and Trends in Most Cited Liver Disease Diagnosis and Treatment Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/liver-disease-diagnosis-and-treatment/2026/rank-4*

| Field | Value |
| --- | --- |
| Rank | #4 |
| 18m citations | 306 |
| Journal | New England Journal of Medicine |
| Year | 2024 |
| DOI | 10.1056/nejmoa2401755 |
| Corresponding authors | Arun J Sanyal |
| Institution | Virginia Commonwealth University, United States |

**Ranking page:** [Topics and Trends in Most Cited Liver Disease Diagnosis and Treatment Papers, Class of 2026](https://pri.pepkio.com/top-papers/liver-disease-diagnosis-and-treatment/2026)

**Paper link:** [10.1056/nejmoa2401755](https://doi.org/10.1056/nejmoa2401755)

## Topics

survodutide · dual agonist · glucagon receptor · GLP-1 receptor · Steatohepatitis · Steatohepatitis · Liver fibrosis · fibrosis stage F1-F3 · histologic improvement · Hepatic steatosis reduction · Liver fibrosis improvement · dose-response relationship · Biopsy-confirmed steatohepatitis · Subcutaneous administration · rapid-dose-escalation phase · nausea · diarrhea · vomiting

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Liver Disease Diagnosis and Treatment Papers, Class of 2026. https://pri.pepkio.com/top-papers/liver-disease-diagnosis-and-treatment/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```