# Gut symbionts alleviate MASH through a secondary bile acid biosynthetic pathway

*PRI Rank #10 · Topics and Trends in Most Cited Liver Disease Diagnosis and Treatment Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/liver-disease-diagnosis-and-treatment/2026/rank-10*

| Field | Value |
| --- | --- |
| Rank | #10 |
| 18m citations | 166 |
| Journal | Cell |
| Year | 2024 |
| DOI | 10.1016/j.cell.2024.03.034 |
| Corresponding authors | Yanxing Jia, Ming‐Hua Zheng, Yanli Pang, Jie Qiao, Changtao Jiang |
| Institution | Peking University, China |

**Ranking page:** [Topics and Trends in Most Cited Liver Disease Diagnosis and Treatment Papers, Class of 2026](https://pri.pepkio.com/top-papers/liver-disease-diagnosis-and-treatment/2026)

**Paper link:** [10.1016/j.cell.2024.03.034](https://doi.org/10.1016/j.cell.2024.03.034)

## Topics

Steatohepatitis · Steatohepatitis · gut microbiota · secondary bile acid · 3-succinylated cholic acid · 3-succinylated cholic acid · click-chemistry-based enrichment · Metabolic dysfunction-associated fatty liver disease · Metabolic dysfunction-associated fatty liver disease · Bacteroides uniformis · β-lactamase · activity-based protein purification · Akkermansia muciniphila · lumen-restricted metabolite · gut-liver axis · microbiota-modified bile acids

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Liver Disease Diagnosis and Treatment Papers, Class of 2026. https://pri.pepkio.com/top-papers/liver-disease-diagnosis-and-treatment/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```