# Acid-degradable lipid nanoparticles enhance the delivery of mRNA

*PRI Rank #9 · Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026/rank-9*

| Field | Value |
| --- | --- |
| Rank | #9 |
| 18m citations | 65 |
| Journal | Nature Nanotechnology |
| Year | 2024 |
| DOI | 10.1038/s41565-024-01765-4 |
| Corresponding authors | Hesong Han, Aijun Wang, Niren Murthy |
| Institution | University of California, Berkeley, United States |

**Ranking page:** [Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026](https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026)

**Paper link:** [10.1038/s41565-024-01765-4](https://doi.org/10.1038/s41565-024-01765-4)

## Topics

acid-degradable lipid nanoparticles · Messenger RNA delivery · Lipid nanoparticles · pH-responsive degradation · nucleic acid delivery · Endosomal release · Transfection efficiency · Ionizable lipids · mRNA therapeutics

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026. https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```