# Charge-assisted stabilization of lipid nanoparticles enables inhaled mRNA delivery for mucosal vaccination

*PRI Rank #3 · Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026/rank-3*

| Field | Value |
| --- | --- |
| Rank | #3 |
| 18m citations | 108 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-53914-x |
| Corresponding authors | Xueguang Lu |
| Institution | Institute of Chemistry, Chinese Academy of Sciences, China |

**Ranking page:** [Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026](https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026)

**Paper link:** [10.1038/s41467-024-53914-x](https://doi.org/10.1038/s41467-024-53914-x)

## Topics

inhaled mRNA delivery · Lipid nanoparticles · charge-assisted stabilization · nebulization · peptide-lipid conjugate · electrostatic repulsion · colloidal stability · pulmonary mRNA delivery · dendritic cells · mucosal immune response · systemic immune response · SARS-CoV-2 Omicron variant · mucosal vaccination · cancer vaccine · lung metastasis · LNP aggregation · Surface charge modification

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026. https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```