# High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles

*PRI Rank #19 · Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026/rank-19*

| Field | Value |
| --- | --- |
| Rank | #19 |
| 18m citations | 41 |
| Journal | Science |
| Year | 2024 |
| DOI | 10.1126/science.adp5577 |
| Corresponding authors | John L. Rubinstein |
| Institution | The Hospital for Sick Children, Canada |

**Ranking page:** [Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026](https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026)

**Paper link:** [10.1126/science.adp5577](https://doi.org/10.1126/science.adp5577)

## Topics

V-ATPase · synaptic vesicles · electron cryomicroscopy · neurotransmitter loading · SidK · V1 complex dissociation · single-particle analysis · cholesterol binding · synaptophysin · ATP hydrolysis · rotor complex · exocytosis · rat brain · native membrane structure · bacterial effector protein

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026. https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```