# Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions

*PRI Rank #13 · Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026/rank-13*

| Field | Value |
| --- | --- |
| Rank | #13 |
| 18m citations | 51 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-49678-z |
| Corresponding authors | Joshua N. Leonard, Neha P. Kamat |
| Institution | Northwestern University, United States |

**Ranking page:** [Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026](https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026)

**Paper link:** [10.1038/s41467-024-49678-z](https://doi.org/10.1038/s41467-024-49678-z)

## Topics

extracellular vesicles · EVs · protein cargo loading · Lipid nanoparticles · plasma membrane trafficking · Lipid rafts · lipid tags · transmembrane proteins · peripheral membrane proteins · protein-lipid interactions · engineered transcription factor · gene expression modulation · functional cargo delivery · therapeutic delivery vehicles · EV-based therapeutics · macromolecular cargo

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026. https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```