# Zinc mediates control of nitrogen fixation via transcription factor filamentation

*PRI Rank #7 · Topics and Trends in Most Cited Legume Nitrogen Fixing Symbiosis Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/legume-nitrogen-fixing-symbiosis/2026/rank-7*

| Field | Value |
| --- | --- |
| Rank | #7 |
| 18m citations | 42 |
| Journal | Nature |
| Year | 2024 |
| DOI | 10.1038/s41586-024-07607-6 |
| Corresponding authors | Jie-shun Lin, Kasper R. Andersen, Dugald Reid |
| Institution | Aarhus University, Denmark |

**Ranking page:** [Topics and Trends in Most Cited Legume Nitrogen Fixing Symbiosis Papers, Class of 2026](https://pri.pepkio.com/top-papers/legume-nitrogen-fixing-symbiosis/2026)

**Paper link:** [10.1038/s41586-024-07607-6](https://doi.org/10.1038/s41586-024-07607-6)

## Topics

Biological nitrogen fixation · zinc signaling · transcription factor filamentation · FIXATION UNDER NITRATE (FUN) · root nodules · Legume-rhizobia symbiosis · soil nitrate sensing · Nodule senescence · zinc-dependent filament assembly · intracellular second messenger · nitrogen homeostasis · zinc concentration readout · FUN transcriptional regulation · nodule breakdown pathways · environmental nitrogen adaptation · metal ion signaling · filament dissociation mechanism · symbiotic nitrogen metabolism

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Legume Nitrogen Fixing Symbiosis Papers, Class of 2026. https://pri.pepkio.com/top-papers/legume-nitrogen-fixing-symbiosis/2026. Accessed 2026-07-29.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```