# Photo‐Controlled Calcium Overload from Endogenous Sources for Tumor Therapy

*PRI Rank #18 · Topics and Trends in Most Cited Ion channel regulation and function Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/ion-channel-regulation-and-function/2026/rank-18*

| Field | Value |
| --- | --- |
| Rank | #18 |
| 18m citations | 29 |
| Journal | Angewandte Chemie International Edition |
| Year | 2024 |
| DOI | 10.1002/anie.202317578 |
| Corresponding authors | Xiaoding Lou, Juyoung Yoon |
| Institution | China University of Geosciences, China |

**Ranking page:** [Topics and Trends in Most Cited Ion channel regulation and function Papers, Class of 2026](https://pri.pepkio.com/top-papers/ion-channel-regulation-and-function/2026)

**Paper link:** [10.1002/anie.202317578](https://doi.org/10.1002/anie.202317578)

## Topics

Calcium overload · reactive calcium-based nanogenerators · photo-controlled calcium nanomodulator · endogenous calcium sources · mesoporous silica nanoparticles · indocyanine green · photodynamic therapy · photothermal therapy · BNN-6 · nitric oxide donor · hyaluronic acid coating · near-infrared light irradiation · reactive oxygen species · TRPA1 channel · calcium influx · Ryanodine receptor type 2 · endoplasmic reticulum calcium release · Calcium overload · tumor cell targeting

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Ion channel regulation and function Papers, Class of 2026. https://pri.pepkio.com/top-papers/ion-channel-regulation-and-function/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```