# GPCR–MAPK signaling pathways underpin fitness trade-offs in whitefly

*PRI Rank #9 · Topics and Trends in Most Cited Insect Resistance and Genetics Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/insect-resistance-and-genetics/2026/rank-9*

| Field | Value |
| --- | --- |
| Rank | #9 |
| 18m citations | 30 |
| Journal | Proceedings of the National Academy of Sciences |
| Year | 2024 |
| DOI | 10.1073/pnas.2402407121 |
| Corresponding authors | Buli Fu, Jinjin Liang, Jinyu Hu, Tianhua Du, Qimei Tan, Chris Bass, Xin Yang, Youjun Zhang |
| Institution | Chinese Academy of Agricultural Sciences, China |

**Ranking page:** [Topics and Trends in Most Cited Insect Resistance and Genetics Papers, Class of 2026](https://pri.pepkio.com/top-papers/insect-resistance-and-genetics/2026)

**Paper link:** [10.1073/pnas.2402407121](https://doi.org/10.1073/pnas.2402407121)

## Topics

GPCR–MAPK signaling pathways · fitness trade-offs · Bemisia tabaci · insecticide resistance · CYP6CM1 · neonicotinoid resistance · p38 MAPK · ERK · cAMP-response element binding protein · CncC · exuperantia (Ex) · vasa (Va) · benign gonial cell neoplasm (Bg) · oogenesis · female fecundity · neuropeptide FF receptor 2 (NPFF2) · positive feedback loop · reproductive cost · cytochrome P450 · cis-trans regulatory networks

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Insect Resistance and Genetics Papers, Class of 2026. https://pri.pepkio.com/top-papers/insect-resistance-and-genetics/2026. Accessed 2026-09-06.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```