# Population suppression by release of insects carrying a dominant sterile homing gene drive targeting doublesex in Drosophila

*PRI Rank #8 · Topics and Trends in Most Cited Insect Resistance and Genetics Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/insect-resistance-and-genetics/2026/rank-8*

| Field | Value |
| --- | --- |
| Rank | #8 |
| 18m citations | 32 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-52473-5 |
| Corresponding authors | Jackson Champer |
| Institution | Peking University, China |

**Ranking page:** [Topics and Trends in Most Cited Insect Resistance and Genetics Papers, Class of 2026](https://pri.pepkio.com/top-papers/insect-resistance-and-genetics/2026)

**Paper link:** [10.1038/s41467-024-52473-5](https://doi.org/10.1038/s41467-024-52473-5)

## Topics

CRISPR homing gene drive · population suppression · doublesex · female sterility · RIDD · fsRIDL · split drive system · 3-gRNA drive · doublesex female exon · germline transmission · resistance alleles · end-joining · Drosophila melanogaster · cage population elimination · male-only release · self-limiting gene drive · SIT comparison · dominant lethal alleles · biased inheritance

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Insect Resistance and Genetics Papers, Class of 2026. https://pri.pepkio.com/top-papers/insect-resistance-and-genetics/2026. Accessed 2026-07-23.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```