# Mechanistic exploration of odorant binding protein-mediated chlorpyrifos resistance in Nilaparvata lugens: Insights from insecticide sequestration and transcriptional regulation

*PRI Rank #12 · Topics and Trends in Most Cited Insect Resistance and Genetics Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/insect-resistance-and-genetics/2026/rank-12*

| Field | Value |
| --- | --- |
| Rank | #12 |
| 18m citations | 28 |
| Journal | International Journal of Biological Macromolecules |
| Year | 2024 |
| DOI | 10.1016/j.ijbiomac.2024.138108 |
| Corresponding authors | Kai Lǚ |
| Institution | Anhui Agricultural University, China |

**Ranking page:** [Topics and Trends in Most Cited Insect Resistance and Genetics Papers, Class of 2026](https://pri.pepkio.com/top-papers/insect-resistance-and-genetics/2026)

**Paper link:** [10.1016/j.ijbiomac.2024.138108](https://doi.org/10.1016/j.ijbiomac.2024.138108)

## Topics

Nilaparvata lugens · odorant binding protein · chlorpyrifos resistance · insecticide sequestration · transcriptional regulation · OBP-mediated resistance · Nilaparvata lugens · organophosphate insecticide · binding affinity · detoxification · gene expression profiling · Ligand binding · resistance mechanism · Molecular docking · insecticide-protein interaction

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Insect Resistance and Genetics Papers, Class of 2026. https://pri.pepkio.com/top-papers/insect-resistance-and-genetics/2026. Accessed 2026-07-23.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```