# Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates

*PRI Rank #9 · Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026/rank-9*

| Field | Value |
| --- | --- |
| Rank | #9 |
| 18m citations | 41 |
| Journal | Science |
| Year | 2024 |
| DOI | 10.1126/science.adj8321 |
| Corresponding authors | Jon M. Steichen, Ivy Phung, Eugenia Salcedo, Gabriel Ozorowski, Andrew B. Ward, Devin Sok, Shane Crotty, William R. Schief |
| Institution | The Scripps Research Institute, United States |

**Ranking page:** [Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026](https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026)

**Paper link:** [10.1126/science.adj8321](https://doi.org/10.1126/science.adj8321)

## Topics

Germline-targeting immunogens · Broadly neutralizing antibodies (bNAbs) · HIV-1 Envelope glycoprotein · N332-GT5 trimer · Heavy chain complementarity-determining region 3 · B cell lineage · B cell lineage · rhesus macaque immunization model · germinal center B cells · B cell lineage · Cryo-electron microscopy · N332 glycan supersite · antibody-antigen recognition · vaccine priming · outbred animal model · B cell lineage · HIV vaccine · trimer-binding interactions · precursor frequency

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026. https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```