# Safety and antiviral effect of a triple combination of HIV-1 broadly neutralizing antibodies: a phase 1/2a trial

*PRI Rank #8 · Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026/rank-8*

| Field | Value |
| --- | --- |
| Rank | #8 |
| 18m citations | 42 |
| Journal | Nature Medicine |
| Year | 2024 |
| DOI | 10.1038/s41591-024-03247-5 |
| Corresponding authors | Boris Jülg, Dan H. Barouch |
| Institution | Ragon Institute, United States |

**Ranking page:** [Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026](https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026)

**Paper link:** [10.1038/s41591-024-03247-5](https://doi.org/10.1038/s41591-024-03247-5)

## Topics

Broadly neutralizing antibodies (bNAbs) · PGT121 · PGDM1400 · VRC07-523LS · triple bNAb combination · Treatment interruption · HIV viral suppression · Viral rebound · bNAb resistance mutations · baseline resistance · immune activation · T cell exhaustion · proinflammatory signaling · CD4 count · serum bNAb concentrations · neutralization coverage · viral escape

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026. https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```