# Virological Failure After Switch to Long-Acting Cabotegravir and Rilpivirine Injectable Therapy: An In-depth Analysis

*PRI Rank #15 · Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026/rank-15*

| Field | Value |
| --- | --- |
| Rank | #15 |
| 18m citations | 35 |
| Journal | Clinical Infectious Diseases |
| Year | 2024 |
| DOI | 10.1093/cid/ciae016 |
| Corresponding authors | Berend J. van Welzen |
| Institution | University Medical Center Utrecht, Netherlands |

**Ranking page:** [Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026](https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026)

**Paper link:** [10.1093/cid/ciae016](https://doi.org/10.1093/cid/ciae016)

## Topics

Long-acting injectable antiretroviral therapy · rilpivirine · Long-acting injectable antiretroviral therapy · Virologic failure · HIV-1 · genotypic resistance testing · NNRTI resistance · NNRTI resistance · INSTI resistance · INSTI resistance · Drug concentrations · trough concentrations · subtherapeutic drug levels · Pharmacokinetic analysis · real-world setting · Maintenance therapy · resistance selection · population cutoff · treatment failure mechanisms

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026. https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```