# Vaccination induces broadly neutralizing antibody precursors to HIV gp41

*PRI Rank #13 · Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026/rank-13*

| Field | Value |
| --- | --- |
| Rank | #13 |
| 18m citations | 36 |
| Journal | Nature Immunology |
| Year | 2024 |
| DOI | 10.1038/s41590-024-01833-w |
| Corresponding authors | Ian A. Wilson, Facundo D. Batista, Shane Crotty, William R. Schief |
| Institution | The Scripps Research Institute, United States |

**Ranking page:** [Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026](https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026)

**Paper link:** [10.1038/s41590-024-01833-w](https://doi.org/10.1038/s41590-024-01833-w)

## Topics

Broadly neutralizing antibodies (bNAbs) · HIV gp41 · 10E8 bnAb · germline-targeting epitope scaffolds · B cell lineage · Heavy chain complementarity-determining region 3 · Heavy chain complementarity-determining region 3 · HIV-1 Envelope glycoprotein · epitope structural mimicry · Nanoparticle multivalent display · naive B cells · rhesus macaques · mRNA-encoded nanoparticles · germline-targeting vaccine design · recessed epitope · 10E8-class precursors · priming immunogens · neutralization breadth

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026. https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```