# Stereotactic Body Radiotherapy vs Sorafenib Alone in Hepatocellular Carcinoma

*PRI Rank #9 · Topics and Trends in Most Cited Hepatocellular Carcinoma Treatment and Prognosis Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/hepatocellular-carcinoma-treatment-and-prognosis/2026/rank-9*

| Field | Value |
| --- | --- |
| Rank | #9 |
| 18m citations | 74 |
| Journal | JAMA Oncology |
| Year | 2024 |
| DOI | 10.1001/jamaoncol.2024.5403 |
| Corresponding authors | Laura A. Dawson |
| Institution | University Health Network-Princess Margaret Cancer Centre, Canada |

**Ranking page:** [Topics and Trends in Most Cited Hepatocellular Carcinoma Treatment and Prognosis Papers, Class of 2026](https://pri.pepkio.com/top-papers/hepatocellular-carcinoma-treatment-and-prognosis/2026)

**Paper link:** [10.1001/jamaoncol.2024.5403](https://doi.org/10.1001/jamaoncol.2024.5403)

## Topics

Hepatocellular carcinoma · locally advanced hepatocellular carcinoma · Stereotactic body radiotherapy · sorafenib · Macrovascular invasion · Overall survival · Progression-free survival · phase 3 randomized clinical trial · First-line treatment · liver function · Locoregional therapy · Stereotactic body radiotherapy · Treatment-related adverse events · Quality of life · hazard ratio · Liver failure · Performance status · Metastatic tumors · Multicenter study · Radiotherapy fractionation · Systemic therapy · early trial termination · standard-of-care systemic therapy · Grade 3 or higher adverse events · stratification factors · Combination therapy

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Hepatocellular Carcinoma Treatment and Prognosis Papers, Class of 2026. https://pri.pepkio.com/top-papers/hepatocellular-carcinoma-treatment-and-prognosis/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```