# Pathological response following neoadjuvant immune checkpoint inhibitors in patients with hepatocellular carcinoma: a cross-trial, patient-level analysis

*PRI Rank #15 · Topics and Trends in Most Cited Hepatocellular Carcinoma Treatment and Prognosis Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/hepatocellular-carcinoma-treatment-and-prognosis/2026/rank-15*

| Field | Value |
| --- | --- |
| Rank | #15 |
| 18m citations | 58 |
| Journal | The Lancet Oncology |
| Year | 2024 |
| DOI | 10.1016/s1470-2045(24)00457-1 |
| Corresponding authors | David J. Pinato |
| Institution | Imperial College London, United Kingdom |

**Ranking page:** [Topics and Trends in Most Cited Hepatocellular Carcinoma Treatment and Prognosis Papers, Class of 2026](https://pri.pepkio.com/top-papers/hepatocellular-carcinoma-treatment-and-prognosis/2026)

**Paper link:** [10.1016/s1470-2045(24)00457-1](https://doi.org/10.1016/s1470-2045(24)00457-1)

## Topics

Hepatocellular carcinoma · Neoadjuvant immunotherapy · Pathological response · Major pathological response · Pathologic complete response · tumour regression · Hepatectomy · relapse-free survival · neoadjuvant therapy · ICI combinations · RECIST 1.1 · Radiologic response · Barcelona Clinic Liver Cancer (BCLC) staging · portal vein thrombosis · viral chronic liver disease · cross-trial patient-level analysis · pooled analysis · phase 1 and 2 clinical trials · NeoHCC consortium · surrogate endpoint · recursive partitioning · tumour regression threshold · 90% tumour regression cutoff · 70% tumour regression cutoff · Neoadjuvant immunotherapy · Performance status · LI-RADS · surgical resection specimen · non-viable tumour percentage · hazard ratio

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Hepatocellular Carcinoma Treatment and Prognosis Papers, Class of 2026. https://pri.pepkio.com/top-papers/hepatocellular-carcinoma-treatment-and-prognosis/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```