# Semaglutide and NT-proBNP in Obesity-Related HFpEF

*PRI Rank #17 · Topics and Trends in Most Cited Heart Failure Treatment and Management Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/heart-failure-treatment-and-management/2026/rank-17*

| Field | Value |
| --- | --- |
| Rank | #17 |
| 18m citations | 63 |
| Journal | Journal of the American College of Cardiology |
| Year | 2024 |
| DOI | 10.1016/j.jacc.2024.04.022 |
| Corresponding authors | Mikhail Kosiborod |
| Institution | University of Glasgow, United Kingdom |

**Ranking page:** [Topics and Trends in Most Cited Heart Failure Treatment and Management Papers, Class of 2026](https://pri.pepkio.com/top-papers/heart-failure-treatment-and-management/2026)

**Paper link:** [10.1016/j.jacc.2024.04.022](https://doi.org/10.1016/j.jacc.2024.04.022)

## Topics

Semaglutide · Natriuretic peptides · Obesity-related HFpEF · Heart failure with preserved ejection fraction · GLP-1 receptor agonist · Obesity · Body weight reduction · STEP-HFpEF trial · STEP-HFpEF DM trial · Type 2 diabetes · KCCQ Clinical Summary Score · health status · Randomized controlled trial · Double-blind randomized controlled trial · Secondary analysis · Natriuretic peptides · Mechanical unloading · HF pathobiology · Biomarker stratification · Secondary analysis · Cardiac wall stress · Weight management · Heart failure symptoms · Functional impairment · Dual primary endpoints · Tertile analysis · Cardiometabolic disease · GLP-1 receptor agonism in heart failure · Obesity-related HFpEF · Biomarker-guided treatment response

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Heart Failure Treatment and Management Papers, Class of 2026. https://pri.pepkio.com/top-papers/heart-failure-treatment-and-management/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```