# Effect of Semaglutide on Cardiac Structure and Function in Patients With Obesity-Related Heart Failure

*PRI Rank #11 · Topics and Trends in Most Cited Heart Failure Treatment and Management Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/heart-failure-treatment-and-management/2026/rank-11*

| Field | Value |
| --- | --- |
| Rank | #11 |
| 18m citations | 94 |
| Journal | Journal of the American College of Cardiology |
| Year | 2024 |
| DOI | 10.1016/j.jacc.2024.08.021 |
| Corresponding authors | Scott D. Solomon |
| Institution | Brigham and Women's Hospital, United States |

**Ranking page:** [Topics and Trends in Most Cited Heart Failure Treatment and Management Papers, Class of 2026](https://pri.pepkio.com/top-papers/heart-failure-treatment-and-management/2026)

**Paper link:** [10.1016/j.jacc.2024.08.021](https://doi.org/10.1016/j.jacc.2024.08.021)

## Topics

Semaglutide · Heart failure with preserved ejection fraction · Obesity-related HFpEF · Obesity · Cardiac remodeling · Left atrial volume · Right ventricular enlargement · Right ventricular enlargement · Right ventricular enlargement · Echocardiography · E-wave velocity · E/A ratio · E/e′ average · diastolic function · Left ventricular mass · Left ventricular systolic function · GLP-1 receptor agonist · weight loss · Body mass index · Type 2 diabetes · atrial fibrillation · STEP-HFpEF trial · Randomized controlled trial · Analysis of covariance (ANCOVA) · Disease-modifying therapy · exercise function · Cardiac structure · Placebo-controlled trial · Mitral inflow velocity · Atrial remodeling

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Heart Failure Treatment and Management Papers, Class of 2026. https://pri.pepkio.com/top-papers/heart-failure-treatment-and-management/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```