# Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway

*PRI Rank #9 · Topics and Trends in Most Cited Gut microbiota and health Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/gut-microbiota-and-health/2026/rank-9*

| Field | Value |
| --- | --- |
| Rank | #9 |
| 18m citations | 128 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-45636-x |
| Corresponding authors | Shu Zhu |
| Institution | Zhejiang University, China |

**Ranking page:** [Topics and Trends in Most Cited Gut microbiota and health Papers, Class of 2026](https://pri.pepkio.com/top-papers/gut-microbiota-and-health/2026)

**Paper link:** [10.1038/s41467-024-45636-x](https://doi.org/10.1038/s41467-024-45636-x)

## Topics

Dubosiella newyorkensis · Clostridium innocuum · DSS-induced colitis · L-Lysine · Aryl hydrocarbon receptor (AhR) · Indoleamine 2,3-dioxygenase · kynurenine pathway · Treg/Th17 balance · dendritic cells · tryptophan catabolism · Short-chain fatty acids · propionate · mucosal barrier · immune tolerance · Gnotobiotic mice · Inflammatory bowel disease

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Gut microbiota and health Papers, Class of 2026. https://pri.pepkio.com/top-papers/gut-microbiota-and-health/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```