# A core microbiome signature as an indicator of health

*PRI Rank #4 · Topics and Trends in Most Cited Gut microbiota and health Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/gut-microbiota-and-health/2026/rank-4*

| Field | Value |
| --- | --- |
| Rank | #4 |
| 18m citations | 175 |
| Journal | Cell |
| Year | 2024 |
| DOI | 10.1016/j.cell.2024.09.019 |
| Corresponding authors | Guojun Wu |
| Institution | Rutgers, The State University of New Jersey, United States |

**Ranking page:** [Topics and Trends in Most Cited Gut microbiota and health Papers, Class of 2026](https://pri.pepkio.com/top-papers/gut-microbiota-and-health/2026)

**Paper link:** [10.1016/j.cell.2024.09.019](https://doi.org/10.1016/j.cell.2024.09.019)

## Topics

Gut microbiome · core microbiome · Metagenomic datasets · high-fiber dietary intervention · type 2 diabetes · co-abundance networks · stably correlated genome pairs · two competing guilds model · fiber fermentation · butyrate production · virulence genes · antibiotic resistance · random forest models · immunotherapy outcome prediction · guild-based approach · systems biology · case-control studies

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Gut microbiota and health Papers, Class of 2026. https://pri.pepkio.com/top-papers/gut-microbiota-and-health/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```