# Changes in acromegaly comorbidities, treatment, and outcome over three decades: a nationwide cohort study

*PRI Rank #14 · Topics and Trends in Most Cited Growth Hormone and Insulin-like Growth Factors Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/growth-hormone-and-insulin-like-growth-factors/2026/rank-14*

| Field | Value |
| --- | --- |
| Rank | #14 |
| 18m citations | 12 |
| Journal | Frontiers in Endocrinology |
| Year | 2024 |
| DOI | 10.3389/fendo.2024.1380436 |
| Corresponding authors | Christian Rosendal |
| Institution | Aalborg University Hospital, Denmark |

**Ranking page:** [Topics and Trends in Most Cited Growth Hormone and Insulin-like Growth Factors Papers, Class of 2026](https://pri.pepkio.com/top-papers/growth-hormone-and-insulin-like-growth-factors/2026)

**Paper link:** [10.3389/fendo.2024.1380436](https://doi.org/10.3389/fendo.2024.1380436)

## Topics

acromegaly · Insulin-like growth factor 1 · Pituitary adenoma · IGF-1 normalization · diabetes · heart disease · sleep apnea · joint disease · Osteoporosis · cancer risk · mortality risk · medical therapy · pituitary surgery · pituitary irradiation · Hypopituitarism · biochemical control · comorbidity burden · Danish nationwide cohort

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Growth Hormone and Insulin-like Growth Factors Papers, Class of 2026. https://pri.pepkio.com/top-papers/growth-hormone-and-insulin-like-growth-factors/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```