# Targeting IGF2 to reprogram the tumor microenvironment for enhanced viro-immunotherapy

*PRI Rank #11 · Topics and Trends in Most Cited Growth Hormone and Insulin-like Growth Factors Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/growth-hormone-and-insulin-like-growth-factors/2026/rank-11*

| Field | Value |
| --- | --- |
| Rank | #11 |
| 18m citations | 15 |
| Journal | Neuro-Oncology |
| Year | 2024 |
| DOI | 10.1093/neuonc/noae105 |
| Corresponding authors | Tae Jin Lee, Ji Young Yoo |
| Institution | The University of Texas Health Science Center at Houston, United States |

**Ranking page:** [Topics and Trends in Most Cited Growth Hormone and Insulin-like Growth Factors Papers, Class of 2026](https://pri.pepkio.com/top-papers/growth-hormone-and-insulin-like-growth-factors/2026)

**Paper link:** [10.1093/neuonc/noae105](https://doi.org/10.1093/neuonc/noae105)

## Topics

Oncolytic herpes simplex-1 virus · Oncolytic herpes simplex-1 virus · Insulin-like growth factor 2 · tumor microenvironment · viro-immunotherapy · Glioblastoma · Glioblastoma · Breast cancer brain metastasis · Breast cancer brain metastasis · rQNestin34.5v.2 · IGF2R domain 11 · IGF2RD11mt · oHSV-D11mt · neutrophils · PMN-MDSCs · CD8+ cytotoxic T lymphocytes · therapy resistance · decoy receptor · RNA-Seq

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Growth Hormone and Insulin-like Growth Factors Papers, Class of 2026. https://pri.pepkio.com/top-papers/growth-hormone-and-insulin-like-growth-factors/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```