# Chemical Synthesis of Human Proteoforms and Application in Biomedicine

*PRI Rank #6 · Topics and Trends in Most Cited Glycosylation and Glycoproteins Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/glycosylation-and-glycoproteins-research/2026/rank-6*

| Field | Value |
| --- | --- |
| Rank | #6 |
| 18m citations | 50 |
| Journal | ACS Central Science |
| Year | 2024 |
| DOI | 10.1021/acscentsci.4c00642 |
| Corresponding authors | Lei Liu |
| Institution | Tsinghua University, China |

**Ranking page:** [Topics and Trends in Most Cited Glycosylation and Glycoproteins Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/glycosylation-and-glycoproteins-research/2026)

**Paper link:** [10.1021/acscentsci.4c00642](https://doi.org/10.1021/acscentsci.4c00642)

## Topics

human proteoforms · chemical synthesis · protein chemical synthesis · post-translational modification · native chemical ligation · expressed protein ligation · desulfurization · peptide synthesis · protein therapeutics · precision diagnostics · functional analysis · mechanistic biochemistry · drug development · synthetic proteins · proteoform therapeutics

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Glycosylation and Glycoproteins Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/glycosylation-and-glycoproteins-research/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```