# Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity

*PRI Rank #4 · Topics and Trends in Most Cited Glycosylation and Glycoproteins Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/glycosylation-and-glycoproteins-research/2026/rank-4*

| Field | Value |
| --- | --- |
| Rank | #4 |
| 18m citations | 63 |
| Journal | Cancer Cell |
| Year | 2024 |
| DOI | 10.1016/j.ccell.2024.11.003 |
| Corresponding authors | Philip D. Greenberg, Guideng Li |
| Institution | Chinese Academy of Medical Sciences & Peking Union Medical College, China |

**Ranking page:** [Topics and Trends in Most Cited Glycosylation and Glycoproteins Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/glycosylation-and-glycoproteins-research/2026)

**Paper link:** [10.1016/j.ccell.2024.11.003](https://doi.org/10.1016/j.ccell.2024.11.003)

## Topics

mannose metabolism · T cell differentiation · Antitumor immunity · metabolic reprogramming · effector T cells · tumor microenvironment · glycolysis · metabolic intervention · T cell activation · Cancer immunotherapy

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Glycosylation and Glycoproteins Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/glycosylation-and-glycoproteins-research/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```