# The variation and evolution of complete human centromeres

*PRI Rank #19 · Topics and Trends in Most Cited Genomics and Phylogenetic Studies Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/genomics-and-phylogenetic-studies/2026/rank-19*

| Field | Value |
| --- | --- |
| Rank | #19 |
| 18m citations | 112 |
| Journal | Nature |
| Year | 2024 |
| DOI | 10.1038/s41586-024-07278-3 |
| Corresponding authors | Evan E. Eichler |
| Institution | University of Washington, United States |

**Ranking page:** [Topics and Trends in Most Cited Genomics and Phylogenetic Studies Papers, Class of 2026](https://pri.pepkio.com/top-papers/genomics-and-phylogenetic-studies/2026)

**Paper link:** [10.1038/s41586-024-07278-3](https://doi.org/10.1038/s41586-024-07278-3)

## Topics

long-read sequencing · centromere assembly · α-satellite higher-order repeats · HORs · Single nucleotide variants · centromeric size variation · DNA methylation · CENP-A chromatin immunoprecipitation · kinetochore position · common chimpanzee · orangutan · macaque · orthologous centromeres · α-satellite HOR turnover · saltatory amplification · phylogenetic reconstruction · p arm · q arm · centromeric recombination · monophyletic origin

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Genomics and Phylogenetic Studies Papers, Class of 2026. https://pri.pepkio.com/top-papers/genomics-and-phylogenetic-studies/2026. Accessed 2026-07-17.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```