# A lethal mitonuclear incompatibility in complex I of natural hybrids

*PRI Rank #8 · Topics and Trends in Most Cited Genetic diversity and population structure Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/genetic-diversity-and-population-structure/2026/rank-8*

| Field | Value |
| --- | --- |
| Rank | #8 |
| 18m citations | 45 |
| Journal | Nature |
| Year | 2024 |
| DOI | 10.1038/s41586-023-06895-8 |
| Corresponding authors | Benjamin M. Moran, Molly Schumer |
| Institution | Stanford University, United States |

**Ranking page:** [Topics and Trends in Most Cited Genetic diversity and population structure Papers, Class of 2026](https://pri.pepkio.com/top-papers/genetic-diversity-and-population-structure/2026)

**Paper link:** [10.1038/s41586-023-06895-8](https://doi.org/10.1038/s41586-023-06895-8)

## Topics

mitonuclear incompatibility · respiratory complex I · swordtail fish · hybrid incompatibility · embryonic lethality · mitochondrial proteome · allelic imbalance · non-additive genetic interactions · accelerated evolution · Introgression · Reproductive isolation · three-gene incompatibility · protein-protein interactions · complex I function · Hybridization · juvenile lethality · mitonuclear coevolution · Epistasis · speciation genetics

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Genetic diversity and population structure Papers, Class of 2026. https://pri.pepkio.com/top-papers/genetic-diversity-and-population-structure/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```