# Refining management strategies for Lennox–Gastaut syndrome: Updated algorithms and practical approaches

*PRI Rank #9 · Topics and Trends in Most Cited Epilepsy research and treatment Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/epilepsy-research-and-treatment/2026/rank-9*

| Field | Value |
| --- | --- |
| Rank | #9 |
| 18m citations | 33 |
| Journal | Epilepsia Open |
| Year | 2024 |
| DOI | 10.1002/epi4.13075 |
| Corresponding authors | Stéphane Auvin |
| Institution | INSERM NeuroDiderot, France |

**Ranking page:** [Topics and Trends in Most Cited Epilepsy research and treatment Papers, Class of 2026](https://pri.pepkio.com/top-papers/epilepsy-research-and-treatment/2026)

**Paper link:** [10.1002/epi4.13075](https://doi.org/10.1002/epi4.13075)

## Topics

Lennox-Gastaut syndrome · Developmental and epileptic encephalopathy · tonic seizures · Drug-resistant epilepsy (DRE) · Antiseizure medication · Cannabidiol · Fenfluramine · Valproate · lamotrigine · rufinamide · clobazam · felbamate · topiramate · ketogenic diet therapy · vagus nerve stimulation · corpus callosotomy · treatment algorithm · Expert consensus recommendations · Adjunctive therapy · Seizure control

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Epilepsy research and treatment Papers, Class of 2026. https://pri.pepkio.com/top-papers/epilepsy-research-and-treatment/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```