# A bifunctional endolytic alginate lyase with two different lyase catalytic domains from Vibrio sp. H204

*PRI Rank #3 · Topics and Trends in Most Cited Enzyme Production and Characterization Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/enzyme-production-and-characterization/2026/rank-3*

| Field | Value |
| --- | --- |
| Rank | #3 |
| 18m citations | 44 |
| Journal | Frontiers in Microbiology |
| Year | 2024 |
| DOI | 10.3389/fmicb.2024.1509599 |
| Corresponding authors | Xiaodan Dong, Fuchuan Li, Lizeng Peng |
| Institution | Shandong Academy of Agricultural Sciences, China |

**Ranking page:** [Topics and Trends in Most Cited Enzyme Production and Characterization Papers, Class of 2026](https://pri.pepkio.com/top-papers/enzyme-production-and-characterization/2026)

**Paper link:** [10.3389/fmicb.2024.1509599](https://doi.org/10.3389/fmicb.2024.1509599)

## Topics

alginate lyase · Aly35 · Vibrio sp. H204 · polysaccharide lyase 7 superfamily · bifunctional enzyme · catalytic domain · Aly35-CD1 · Aly35-CD2 · β-elimination · polymannuronate · polyguluronate · unsaturated oligosaccharides · M-blocks · G-blocks · PG-degrading activity · PM-degrading activity · endolytic activity · truncated proteins · bioactive oligosaccharides

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Enzyme Production and Characterization Papers, Class of 2026. https://pri.pepkio.com/top-papers/enzyme-production-and-characterization/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```