# Comparative genomic analysis of thermophilic fungi reveals convergent evolutionary adaptations and gene losses

*PRI Rank #19 · Topics and Trends in Most Cited Enzyme Production and Characterization Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/enzyme-production-and-characterization/2026/rank-19*

| Field | Value |
| --- | --- |
| Rank | #19 |
| 18m citations | 22 |
| Journal | Communications Biology |
| Year | 2024 |
| DOI | 10.1038/s42003-024-06681-w |
| Corresponding authors | Igor V. Grigoriev |
| Institution | US Department of Energy Joint Genome Institute, United States |

**Ranking page:** [Topics and Trends in Most Cited Enzyme Production and Characterization Papers, Class of 2026](https://pri.pepkio.com/top-papers/enzyme-production-and-characterization/2026)

**Paper link:** [10.1038/s42003-024-06681-w](https://doi.org/10.1038/s42003-024-06681-w)

## Topics

thermophilic fungi · Chaetomiaceae · Thermoascaceae · Trichocomaceae · Mucoromycota · thermostable enzymes · Carbohydrate-active enzymes · Endo-1,4-β-xylanase · secondary metabolism · core genome reduction · GC3 content · effective number of codons · Support Vector Machine classifier · Pfam domains · AlphaFold2 · GH10 · disulfide bonds · Ancestral sequence reconstruction · O-methyltransferases · Eurotiomycetes

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Enzyme Production and Characterization Papers, Class of 2026. https://pri.pepkio.com/top-papers/enzyme-production-and-characterization/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```