# The ribotoxic stress response drives UV-mediated cell death

*PRI Rank #6 · Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026/rank-6*

| Field | Value |
| --- | --- |
| Rank | #6 |
| 18m citations | 69 |
| Journal | Cell |
| Year | 2024 |
| DOI | 10.1016/j.cell.2024.05.018 |
| Corresponding authors | Alban Ordureau, Sergi Regot, Rachel Green |
| Institution | Johns Hopkins University School of Medicine, United States |

**Ranking page:** [Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026](https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026)

**Paper link:** [10.1016/j.cell.2024.05.018](https://doi.org/10.1016/j.cell.2024.05.018)

## Topics

ultraviolet radiation · ribotoxic stress response · DNA damage response · ribosomal collisions · ZAK kinase · UV-induced apoptosis · time-resolved phosphoproteomics · GCN2 · negative-feedback modules · phosphodegron autophosphorylation · ZAK degradation · Chemogenetic approach · single-cell imaging · RNA damage · cell fate determination · homeostasis-tolerance-death regimes · nucleic acid damage sentinel

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026. https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```