# Transcription-coupled DNA–protein crosslink repair by CSB and CRL4CSA-mediated degradation

*PRI Rank #20 · Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026/rank-20*

| Field | Value |
| --- | --- |
| Rank | #20 |
| 18m citations | 37 |
| Journal | Nature Cell Biology |
| Year | 2024 |
| DOI | 10.1038/s41556-024-01394-y |
| Corresponding authors | Jurgen A. Marteijn |
| Institution | Erasmus University Medical Center, Netherlands |

**Ranking page:** [Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026](https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026)

**Paper link:** [10.1038/s41556-024-01394-y](https://doi.org/10.1038/s41556-024-01394-y)

## Topics

DNA-protein crosslinks (DPCs) · DPCs · Transcription-coupled DPC repair · Transcription-coupled DPC repair · CSB · CSA · CRL4CSA · RNA polymerase II · Transcription-coupled repair · TC-NER · SPRTN · proteasome-mediated degradation · UVSSA · XPA · E3 ubiquitin ligase · DPC-stalled RNA polymerase II · proteolysis-mediated DPC removal · transcription-blocking DPCs · active gene repair

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026. https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```