# Mechanism of BRCA1–BARD1 function in DNA end resection and DNA protection

*PRI Rank #13 · Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026/rank-13*

| Field | Value |
| --- | --- |
| Rank | #13 |
| 18m citations | 43 |
| Journal | Nature |
| Year | 2024 |
| DOI | 10.1038/s41586-024-07909-9 |
| Corresponding authors | Petr Ćejka |
| Institution | Università della Svizzera italiana, Switzerland |

**Ranking page:** [Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026](https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026)

**Paper link:** [10.1038/s41586-024-07909-9](https://doi.org/10.1038/s41586-024-07909-9)

## Topics

BRCA1–BARD1 · DNA end resection · Homologous recombination · double-strand break repair · EXO1 nuclease · DNA2 nuclease · WRN helicase · Bloom helicase · MRN complex · phosphorylated CtIP · BRCA1–C complex · BRCT repeats · CtIP S327A mutation · 53BP1 · RAD51 · Replication fork protection · DNA end resection · Non-homologous end joining · Replication stress

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026. https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```