# Early oxidative stress and DNA damage in Aβ-burdened hippocampal neurons in an Alzheimer’s-like transgenic rat model

*PRI Rank #12 · Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026/rank-12*

| Field | Value |
| --- | --- |
| Rank | #12 |
| 18m citations | 45 |
| Journal | Communications Biology |
| Year | 2024 |
| DOI | 10.1038/s42003-024-06552-4 |
| Corresponding authors | A. Claudio Cuello, Sonia Do Carmo |
| Institution | McGill University, Canada |

**Ranking page:** [Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026](https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026)

**Paper link:** [10.1038/s42003-024-06552-4](https://doi.org/10.1038/s42003-024-06552-4)

## Topics

intraneuronal amyloid beta · McGill-R-Thy1-APP transgenic rat · laser microdissection · hippocampal neurons · pre-plaque oxidative stress · DNA double stranded breaks · γH2AX foci · Ercc2 · Fancc · Sod2 · Gsr · Idh1 · XPD · Ercc6 · RAD51 · Fen1 · Sirt6 · Grin2b · TOP2β · maladaptive synaptic plasticity

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026. https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```