# The impact of weight loss on fat-free mass, muscle, bone and hematopoiesis health: Implications for emerging pharmacotherapies aiming at fat reduction and lean mass preservation

*PRI Rank #13 · Topics and Trends in Most Cited Diet and metabolism studies Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/diet-and-metabolism-studies/2026/rank-13*

| Field | Value |
| --- | --- |
| Rank | #13 |
| 18m citations | 102 |
| Journal | Metabolism |
| Year | 2024 |
| DOI | 10.1016/j.metabol.2024.156057 |
| Corresponding authors | Konstantinos Stefanakis |
| Institution | Beth Israel Deaconess Medical Center, United States |

**Ranking page:** [Topics and Trends in Most Cited Diet and metabolism studies Papers, Class of 2026](https://pri.pepkio.com/top-papers/diet-and-metabolism-studies/2026)

**Paper link:** [10.1016/j.metabol.2024.156057](https://doi.org/10.1016/j.metabol.2024.156057)

## Topics

weight loss · Lean body mass · Muscle mass preservation · bone health · hematopoiesis · pharmacotherapies · Weight loss · Muscle mass preservation · body composition · skeletal muscle · bone mineral density · sarcopenia · cachexia · GLP-1 receptor agonists · dual-energy X-ray absorptiometry · protein turnover · myokines · osteoblast activity · bone marrow adiposity · anabolic resistance

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Diet and metabolism studies Papers, Class of 2026. https://pri.pepkio.com/top-papers/diet-and-metabolism-studies/2026. Accessed 2026-07-23.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```