# A Randomized Trial of Intravenous Amino Acids for Kidney Protection

*PRI Rank #4 · Topics and Trends in Most Cited Dialysis and Renal Disease Management Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/dialysis-and-renal-disease-management/2026/rank-4*

| Field | Value |
| --- | --- |
| Rank | #4 |
| 18m citations | 130 |
| Journal | New England Journal of Medicine |
| Year | 2024 |
| DOI | 10.1056/nejmoa2403769 |
| Corresponding authors | Giovanni Landoni |
| Institution | IRCCS San Raffaele Scientific Institute, Italy |

**Ranking page:** [Topics and Trends in Most Cited Dialysis and Renal Disease Management Papers, Class of 2026](https://pri.pepkio.com/top-papers/dialysis-and-renal-disease-management/2026)

**Paper link:** [10.1056/nejmoa2403769](https://doi.org/10.1056/nejmoa2403769)

## Topics

Intravenous amino acid therapy · Acute kidney injury · cardiac surgery · cardiopulmonary bypass · kidney perfusion · renal functional reserve · KDIGO creatinine criteria · Kidney replacement therapy · Ringer's solution placebo · balanced amino acid mixture · ideal body weight dosing · Stage 3 acute kidney injury · 30-day mortality · Randomized double-blind placebo-controlled trial · PROTECTION trial · NCT03709264

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Dialysis and Renal Disease Management Papers, Class of 2026. https://pri.pepkio.com/top-papers/dialysis-and-renal-disease-management/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```